Search results for " tools"
showing 10 items of 331 documents
Minimal clinically important difference and minimal detectable change of the World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0…
2020
Objectives: The aim of this study is to estimate a minimal clinically important difference (MCID) and a minimal detectable change (MDC) of the 12-item WHODAS 2.0 amongst patients with chronic musculoskeletal pain. Design: Cross-sectional cohort study. Setting: Outpatient Physical and Rehabilitation Medicine clinic. Subjects: A total of 1988 consecutive patients with musculoskeletal pain. Interventions: A distribution-based approach was employed to estimate a minimal clinically important difference, a minimal detectable change, and a minimal detectable percent change (MDC%). Results: The mean age of the patients was 48 years, and 65% were women. The average intensity of pain was 6,3 (2.0) po…
Planning integrated care at primary care centres: lessons learnt through research in stratification tools in the Valencian Healthcare System
2018
Introduction and policy context: In the Valencian Region social services and the healthcare system are not connected. Also there is not any normative jointly regulating resources, services or aid benefits that would mean an integrated care IC portfolio. Primary care PC centres are the closest and most trustworthy care facility for patients in the Spanish context. Also, PC is one of the most suitable resources to address needs of complex patients, as elderly and/or those with chronic conditions, through an IC approach, but there are some barriers that block its real and effective deployment. Objective and target population: Authors have studied the viability, implementation and development …
Damping in quantum love affairs
2011
In a series of recent papers we have used an operatorial technique to describe stock markets and, in a different context, {\em love affairs} and their time evolutions. The strategy proposed so far does not allow any dumping effect. In this short note we show how, within the same framework, a strictly non periodic or quasi-periodic effect can be introduced in the model by describing in some details a linear Alice-Bob love relation with damping.
Heat shock response in yeast involver changes in both transcription rates and mRNA stabilities
2011
We have analyzed the heat stress response in the yeast Saccharomyces cerevisiae by determining mRNA levels and transcription rates for the whole transcriptome after a shift from 25uC to 37uC. Using an established mathematical algorithm, theoretical mRNA decay rates have also been calculated from the experimental data. We have verified the mathematical predictions for selected genes by determining their mRNA decay rates at different times during heat stress response using the regulatable tetO promoter. This study indicates that the yeast response to heat shock is not only due to changes in transcription rates, but also to changes in the mRNA stabilities. mRNA stability is affected in 62% of …
On the origin of European sheep as revealed by the diversity of the Balkan breeds and by optimizing population-genetic analysis tools
2020
Background In the Neolithic, domestic sheep migrated into Europe and subsequently spread in westerly and northwesterly directions. Reconstruction of these migrations and subsequent genetic events requires a more detailed characterization of the current phylogeographic differentiation. Results We collected 50 K single nucleotide polymorphism (SNP) profiles of Balkan sheep that are currently found near the major Neolithic point of entry into Europe, and combined these data with published genotypes from southwest-Asian, Mediterranean, central-European and north-European sheep and from Asian and European mouflons. We detected clines, ancestral components and admixture by using variants of commo…
16S rRNA sequences as diagnostic tools to elucidate potential symbiotic relationships between bacteria and the marine sponge Halichondria panicea : r…
1999
Does pain intensity predict a poor opioid response in cancer patients?
2011
Abstract Aim The aim of this study was to test the hypothesis that initial pain intensity is not a predictive factor of poor opioid response in advanced cancer patients, as suggested by a recent work. Methods A secondary analysis of one-hundred-sixty-seven patients referred for treatment of cancer-related pain was conducted. Pain intensity at admission was recorded and patients were divided in three categories of pain intensity: mild, moderate and severe. Patients were offered a treatment with opioid dose titration, according to department policy. Data regarding opioid doses and pain intensity were collected after dose titration was completed. Four levels of opioid response were considered:…
Forest management planning at different geographic levels in Italy: hierarchy, current tools and ongoing development
2009
This paper examines the current status of forest management tools and their pplication at different levels in Italy where the majority of land planning has been and is still being done at the “micro-scale”, meaning that specific local issues are dealt with locally. Starting from international European Union law, the authors review the forest acts that led from the National Forest Plan (NFP) to smaller scales, in relation to their geographic and territorial applicability. Scaling down from the NFP to the local level the various Italian forest programmes and plans are analysed according to a vertical logic (hierarchical mode): Regional Forest Programme (RFP), Territorial (i.e. sub-regional) F…
Integrating the Tumor Microenvironment into Cancer Therapy
2020
© 2020 by the authors.
Electronic system for assessing and analysing digital competences in the context of Knowledge Society
2019
The digital competencies of users, in general, and of public administration personnel, in particular, must allow the people access to graphical interfaces and applications, including databases. The use of digital competences is not simply about the emergence and use of computer tools to a certain level but also to develop new digital skills to face the challenges of data quality, responsibility, confidence in information received, the privacy of the user and the safety of its data. The study tool in this paper is managed and applied online, and the collection and centralization of data is done automatically, also ensuring information security. The basic method used in this paper is the mode…